I struggle hard with this stuff. The usual SSRIs tends to make me function on a surface getting-through-the-day level far better than I do without them, and I need a pretty high dose on the whole. What I don't really get is anything much else, while usually I'd have stuff going on on a whole lot of different levels at once, and after a while it really gets to me. (It is possibly telling that many years back, my first and biggest bout of self-harming took place after I'd been put on drugs rather than before. Er.)